Daily low-intensity pulsed ultrasound-mediated osteogenic differentiation in rat osteoblasts

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Daily low-intensity pulsed ultrasound-mediated osteogenic differentiation in rat osteoblasts.

There were few studies investigating the effects of the mechanical stimulation provided by daily low-intensity pulsed ultrasound (LIPUS) treatment. LIPUS is known to accelerate bone mineralization and regeneration; however, the precise cellular mechanism is unclear.Our purpose was to determine how daily LIPUS treatment affected cell viability, alkaline phosphatase activity, osteogenesis-related...

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Low-intensity pulsed ultrasound (LIPUS) as an adjuvant therapy in in vitro and in vivo bone engineering has proven to be extremely useful. The present study aimed at investigating the effect of 30 mW/cm2 LIPUS stimulation on commercially available human mesenchymal stem cells (hMSCs) cultured in basal or osteogenic medium at different experimental time points (7, 14, 21 days). The hypothesis wa...

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Low Intensity Pulsed Ultrasound (LIPUS)

The application of ultrasound energy at much lower levels than is the current clinical norm is starting to gain ground as a therapeutic possibility. Clearly the applied energy is the same, it is the ‘dose’ which is different – most importantly, the intensity (W cm) – which is MUCH lower – typically 2 or 3 times lower than the lowest setting on most regular clinical machines, with the most commo...

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ژورنال

عنوان ژورنال: Acta Biochimica et Biophysica Sinica

سال: 2009

ISSN: 1672-9145,1745-7270

DOI: 10.1093/abbs/gmn012